Spiriva Respimat Approved for maintenance of COPD

"Boehringer Ingelheim announced that the US regulatory body has approved Spiriva Respimat (tiotropium bromide) inhalation spray for the long-term, once-daily maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease (COPD)."
According to the Pharmaceutical Journal, Spiriva Respimat (tiotropium bromide monohydrate; Boehringer Ingelheim) is now recommended as an add-on preventive therapy. It is for adult asthma patients currently being treated with a maintenance combination of inhaled corticosteroids and long-acting β2 agonists who already had one or more serious exacerbations in the previous year.

Spiriva Respimat releases a pre-measured dosage in a slow-moving spray, irrespective of how easily air from the inhaler is breathed in. The Respimat inhaler creates the slow-moving mist through mechanical energy. Spiriva Respimat solution uses the same element as Spiriva HandiHaler (inhalation material for tiotropium bromide) as stated by MPR publications.

It also states that Spiriva Respimat's approval was based on data from seven clinical trials in which Spiriva Respimat handled 8,700 people. TIOSPIR collected data from over 5,700 patients treated with Spiriva Respimat and all 5,700 patients treated with Spiriva HandiHaler at one of these experiments. The generic medications of Spiriva Respimat are Tiotropium.

According to the recall guide, when used with the Spiriva Respimat inhaler, per cartridge comprising 4 grams of sterile aqueous solution contains 60 (or 28) metered actuation upon preparation for use, the equivalent of 30-day (or 14-day) treatment when used once a day with two actuations.

Each dosage (one dose equals two actuations) from the SPIRIVA RESPIMAT inhaler is supplied from the mouthpiece with 5 mcg of tiotropium in 22.1 mcL. As with all inhaled medications, the actual amount of prescription medications administered to the lung may rely on patient conditions such as synchronization through the delivery system between inhaler action and inspiration.

NOTE: This sheet is a summary. It may not cover all possible information. If you have questions about this medicine, talk to your doctor, pharmacist, or health care provider. 

DISCLAIMER: This content is provided for informational purposes only. The content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Patients should always consult their physicians with any questions regarding a medical condition and to obtain medical advice and treatment.